What if a cure existed for cancer, diabetes, heart disease, blindness, HIV/AIDS, and many other debilitating diseases and illnesses? Adapted into state law in the 2004, the California Stem Cell Research and Cures Act directs $3 billion of state monies toward stem cell research to make such cures a reality. Also, the investment into biotech is predicted to create up to 22,000 jobs on average a year.To facilitate active and informed participation, this brief raises important policy issues related to stem cell research such as: Who will receive the $3 billion in the form of grants and jobs? How will the state reap the economic benefits promised by the California Stem Cell Research and Cures Act? How might the public and private industry create win-win situations to mutually profit from stem cell research?